Silymarin-loaded solid nanoparticles provide excellent hepatic protection: physicochemical characterization and in vivo evaluation

BACKGROUND: The purpose of this study was to develop a novel silymarin-loaded solid nanoparticle system with enhanced oral bioavailability and an ability to provide excellent hepatic protection for poorly water-soluble drugs using Shirasu porous glass (SPG) membrane emulsification and a spray-drying...

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Detalhes bibliográficos
Main Authors: Yang, Kwan Yeol, Hwang, Du Hyeong, Yousaf, Abid Mehmood, Kim, Dong Wuk, Shin, Young-Jun, Bae, Ok-Nam, Kim, Yong-II, Kim, Jong Oh, Yong, Chul Soon, Choi, Han-Gon
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2013
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3770518/
https://ncbi.nlm.nih.gov/pubmed/24039417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S50683
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