Aurora kinase A has a significant role as a therapeutic target and clinical biomarker in endometrial cancer

Aurora kinase A (AURKA) regulates the cell cycle checkpoint and maintains genomic integrity. AURKA is overexpressed in various malignant tumors and its upregulation induces chromosomal instability, which leads to aneuploidy and cell transformation. To investigate the role of AURKA in endometrial can...

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Dettagli Bibliografici
Pubblicato in:Int J Oncol
Autori principali: UMENE, KIYOKO, YANOKURA, MEGUMI, BANNO, KOUJI, IRIE, HARUKO, ADACHI, MASATAKA, IIDA, MIHO, NAKAMURA, KANAKO, NOGAMI, YUYA, MASUDA, KENTA, KOBAYASHI, YUSUKE, TOMINAGA, EIICHIRO, AOKI, DAISUKE
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2015
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356503/
https://ncbi.nlm.nih.gov/pubmed/25625960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2015.2842
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