Aurora kinase A has a significant role as a therapeutic target and clinical biomarker in endometrial cancer

Aurora kinase A (AURKA) regulates the cell cycle checkpoint and maintains genomic integrity. AURKA is overexpressed in various malignant tumors and its upregulation induces chromosomal instability, which leads to aneuploidy and cell transformation. To investigate the role of AURKA in endometrial can...

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Publicat a:Int J Oncol
Autors principals: UMENE, KIYOKO, YANOKURA, MEGUMI, BANNO, KOUJI, IRIE, HARUKO, ADACHI, MASATAKA, IIDA, MIHO, NAKAMURA, KANAKO, NOGAMI, YUYA, MASUDA, KENTA, KOBAYASHI, YUSUKE, TOMINAGA, EIICHIRO, AOKI, DAISUKE
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2015
Matèries:
Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356503/
https://ncbi.nlm.nih.gov/pubmed/25625960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2015.2842
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