Aurora kinase A has a significant role as a therapeutic target and clinical biomarker in endometrial cancer

Aurora kinase A (AURKA) regulates the cell cycle checkpoint and maintains genomic integrity. AURKA is overexpressed in various malignant tumors and its upregulation induces chromosomal instability, which leads to aneuploidy and cell transformation. To investigate the role of AURKA in endometrial can...

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Udgivet i:Int J Oncol
Main Authors: UMENE, KIYOKO, YANOKURA, MEGUMI, BANNO, KOUJI, IRIE, HARUKO, ADACHI, MASATAKA, IIDA, MIHO, NAKAMURA, KANAKO, NOGAMI, YUYA, MASUDA, KENTA, KOBAYASHI, YUSUKE, TOMINAGA, EIICHIRO, AOKI, DAISUKE
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2015
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356503/
https://ncbi.nlm.nih.gov/pubmed/25625960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2015.2842
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