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Aurora kinase A has a significant role as a therapeutic target and clinical biomarker in endometrial cancer

Aurora kinase A (AURKA) regulates the cell cycle checkpoint and maintains genomic integrity. AURKA is overexpressed in various malignant tumors and its upregulation induces chromosomal instability, which leads to aneuploidy and cell transformation. To investigate the role of AURKA in endometrial can...

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Detalhes bibliográficos
Publicado no:Int J Oncol
Main Authors: UMENE, KIYOKO, YANOKURA, MEGUMI, BANNO, KOUJI, IRIE, HARUKO, ADACHI, MASATAKA, IIDA, MIHO, NAKAMURA, KANAKO, NOGAMI, YUYA, MASUDA, KENTA, KOBAYASHI, YUSUKE, TOMINAGA, EIICHIRO, AOKI, DAISUKE
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356503/
https://ncbi.nlm.nih.gov/pubmed/25625960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2015.2842
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