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Role of Drosophila EDEMs in the degradation of the alpha-1-antitrypsin Z variant

The synthesis of proteins in the endoplasmic reticulum (ER) that exceeds the protein folding capacity of this organelle is a frequent cause of cellular dysfunction and disease. An example of such a disease is alpha-1-antitrypsin (A1AT) deficiency, caused by destabilizing mutations in this glycoprote...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Int J Mol Med
Päätekijät: JANG, BO-YUN, RYOO, HYUNG DON, SON, JAEKYOUNG, CHOI, KYUNG-CHUL, SHIN, DONG-MYOUNG, KANG, SANG-WOOK, KANG, MIN-JI
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: D.A. Spandidos 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356437/
https://ncbi.nlm.nih.gov/pubmed/25716426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2015.2109
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