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Role of Drosophila EDEMs in the degradation of the alpha-1-antitrypsin Z variant
The synthesis of proteins in the endoplasmic reticulum (ER) that exceeds the protein folding capacity of this organelle is a frequent cause of cellular dysfunction and disease. An example of such a disease is alpha-1-antitrypsin (A1AT) deficiency, caused by destabilizing mutations in this glycoprote...
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| Udgivet i: | Int J Mol Med |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
D.A. Spandidos
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4356437/ https://ncbi.nlm.nih.gov/pubmed/25716426 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2015.2109 |
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