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Structural characterization of substrate and inhibitor binding to farnesyl pyrophosphate synthase from Pseudomonas aeruginosa

Locus PA4043 in the genome of Pseudomonas aeruginosa PAO1 has been annotated as coding for a farnesyl pyrophosphate synthase (FPPS). This open reading frame was cloned and expressed recombinantly in Escherichia coli. The dimeric enzyme shows farnesyl pyrophosphate synthase activity and is strongly i...

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Bibliografische gegevens
Gepubliceerd in:Acta Crystallogr D Biol Crystallogr
Hoofdauteurs: Schmidberger, Jason W., Schnell, Robert, Schneider, Gunter
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: International Union of Crystallography 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356374/
https://ncbi.nlm.nih.gov/pubmed/25760619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1399004715001121
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