Tetrahydrodipicolinate N-Succinyltransferase and Dihydrodipicolinate Synthase from Pseudomonas aeruginosa: Structure Analysis and Gene Deletion

The diaminopimelic acid pathway of lysine biosynthesis has been suggested to provide attractive targets for the development of novel antibacterial drugs. Here we report the characterization of two enzymes from this pathway in the human pathogen Pseudomonas aeruginosa, utilizing structural biology, b...

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Autori principali: Schnell, Robert, Oehlmann, Wulf, Sandalova, Tatyana, Braun, Yvonne, Huck, Carmen, Maringer, Marko, Singh, Mahavir, Schneider, Gunter
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281039/
https://ncbi.nlm.nih.gov/pubmed/22359568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031133
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