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Substrate Channel Flexibility in Pseudomonas aeruginosa MurB Accommodates Two Distinct Substrates
Biosynthesis of UDP-N-acetylmuramic acid in bacteria is a committed step towards peptidoglycan production. In an NADPH- and FAD-dependent reaction, the UDP-N-acetylglucosamine-enolpyruvate reductase (MurB) reduces UDP-N-acetylglucosamine-enolpyruvate to UDP-N-acetylmuramic acid. We determined the th...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3689657/ https://ncbi.nlm.nih.gov/pubmed/23805286 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066936 |
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