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Translesion Polymerase Genes Polymorphisms and Haplotypes Influence Survival of Osteosarcoma Patients

Cytotoxic activity of most chemotherapeutic agents is based on their ability to induce DNA damage. Interstrand crosslinks are among the most detrimental forms of DNA damage as both DNA strands are affected. As translesion polymerases participate in their repair, they may be important for response to...

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Detalles Bibliográficos
Publicado en:OMICS
Main Authors: Goričar, Katja, Kovač, Viljem, Jazbec, Janez, Zakotnik, Branko, Lamovec, Janez, Dolžan, Vita
Formato: Artigo
Idioma:Inglês
Publicado: Mary Ann Liebert, Inc. 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356257/
https://ncbi.nlm.nih.gov/pubmed/25748439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/omi.2014.0159
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