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Translesion Polymerase Genes Polymorphisms and Haplotypes Influence Survival of Osteosarcoma Patients

Cytotoxic activity of most chemotherapeutic agents is based on their ability to induce DNA damage. Interstrand crosslinks are among the most detrimental forms of DNA damage as both DNA strands are affected. As translesion polymerases participate in their repair, they may be important for response to...

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Detalhes bibliográficos
Publicado no:OMICS
Main Authors: Goričar, Katja, Kovač, Viljem, Jazbec, Janez, Zakotnik, Branko, Lamovec, Janez, Dolžan, Vita
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356257/
https://ncbi.nlm.nih.gov/pubmed/25748439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/omi.2014.0159
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