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Translesion Polymerase Genes Polymorphisms and Haplotypes Influence Survival of Osteosarcoma Patients

Cytotoxic activity of most chemotherapeutic agents is based on their ability to induce DNA damage. Interstrand crosslinks are among the most detrimental forms of DNA damage as both DNA strands are affected. As translesion polymerases participate in their repair, they may be important for response to...

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書目詳細資料
發表在:OMICS
Main Authors: Goričar, Katja, Kovač, Viljem, Jazbec, Janez, Zakotnik, Branko, Lamovec, Janez, Dolžan, Vita
格式: Artigo
語言:Inglês
出版: Mary Ann Liebert, Inc. 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356257/
https://ncbi.nlm.nih.gov/pubmed/25748439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/omi.2014.0159
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