Heteroclitic XBP1 peptides evoke tumor-specific memory cytotoxic T lymphocytes against breast cancer, colon cancer, and pancreatic cancer cells

XBP1 is a critical transcriptional activator of the unfolded protein response (UPR), which increases tumor cell survival under prolonged endoplasmic reticulum (ER) stress and hypoxic conditions.This study was designed to evaluate the immunogenicity of heteroclitic XBP1 unspliced (US)(184–192) (YISPW...

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發表在:Oncoimmunology
Main Authors: Bae, Jooeun, Samur, Mehmet, Munshi, Aditya, Hideshima, Teru, Keskin, Derin, Kimmelman, Alec, Lee, Ann-Hwee, Dranoff, Glen, Anderson, Kenneth C, Munshi, Nikhil C
格式: Artigo
語言:Inglês
出版: Taylor & Francis 2015
主題:
Original Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356023/
https://ncbi.nlm.nih.gov/pubmed/25941601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21624011.2014.970914
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