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Heteroclitic XBP1 peptides evoke tumor-specific memory cytotoxic T lymphocytes against breast cancer, colon cancer, and pancreatic cancer cells

XBP1 is a critical transcriptional activator of the unfolded protein response (UPR), which increases tumor cell survival under prolonged endoplasmic reticulum (ER) stress and hypoxic conditions.This study was designed to evaluate the immunogenicity of heteroclitic XBP1 unspliced (US)(184–192) (YISPW...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Bae, Jooeun, Samur, Mehmet, Munshi, Aditya, Hideshima, Teru, Keskin, Derin, Kimmelman, Alec, Lee, Ann-Hwee, Dranoff, Glen, Anderson, Kenneth C, Munshi, Nikhil C
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356023/
https://ncbi.nlm.nih.gov/pubmed/25941601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21624011.2014.970914
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