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Selective Targeting of Multiple Myeloma by B cell Maturation Antigen (BCMA)-specific Central Memory CD8(+) Cytotoxic T Lymphocytes: Immunotherapeutic Application in Vaccination and Adoptive Immunotherapy

To expand the breadth and extent of current multiple myeloma (MM)-specific immunotherapy, we have identified various antigens on CD138+ tumor cells from newly diagnosed MM patients (n=616) and confirmed B-cell Maturation Antigen (BCMA) as a key myeloma-associated antigen. The aim of this study is to...

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Dettagli Bibliografici
Pubblicato in:Leukemia
Autori principali: Bae, Jooeun, Samur, Mehmet, Richardson, Paul, Munshi, Nikhil C., Anderson, Kenneth C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6728221/
https://ncbi.nlm.nih.gov/pubmed/30872779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-019-0414-z
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