Identification and characterization of HLA-A24 specific XBP1, CD138 (Syndecan-1), and CS1 (SLAMF7) peptides inducing antigens-specific memory cytotoxic T lymphocytes targeting multiple myeloma

XBP1 (X-box binding protein 1), CD138 (Syndecan-1), and CS1 (SLAMF7) are highly expressed antigens in cancers including multiple myeloma (MM). Here we identify and characterize immunogenic HLA-A24 peptides derived from these antigens for potential vaccination therapy of HLA-A24+ patients with MM. Th...

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Detalhes bibliográficos
Publicado no:Leukemia
Main Authors: Bae, Jooeun, Hideshima, Teru, Zhang, Guanglan Lan, Zhou, Jun, Keskin, Derin B., Munshi, Nikhil C., Anderson, Kenneth C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5953209/
https://ncbi.nlm.nih.gov/pubmed/29089645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2017.316
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