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Removing batch effects from purified plasma cell gene expression microarrays with modified ComBat

BACKGROUND: Gene expression profiling (GEP) via microarray analysis is a widely used tool for assessing risk and other patient diagnostics in clinical settings. However, non-biological factors such as systematic changes in sample preparation, differences in scanners, and other potential batch effect...

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Bibliografische gegevens
Gepubliceerd in:BMC Bioinformatics
Hoofdauteurs: Stein, Caleb K, Qu, Pingping, Epstein, Joshua, Buros, Amy, Rosenthal, Adam, Crowley, John, Morgan, Gareth, Barlogie, Bart
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355992/
https://ncbi.nlm.nih.gov/pubmed/25887219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-015-0478-3
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