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An Evaluation of Gene Set Analysis for Biomarker Discovery with Applications to Myeloma Research

In this paper, we evaluate 15 methods for gene set analysis in microarray classification problems. We employ four datasets from myeloma research and three types of biological gene sets, encompassing a total of 12 scenarios. Taking a two-step approach, we first identify important genes within gene se...

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Publié dans:Frontiers of Biostatistical Methods and Applications in Clinical Oncology
Auteurs principaux: Qu, Pingping, Tian, Erming, Barlogie, Bart, Morgan, Gareth, Crowley, John
Format: Artigo
Langue:Inglês
Publié: 2017
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7120714/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-981-10-0126-0_25
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