Genome-wide DNA methylation analysis reveals estrogen-mediated epigenetic repression of metallothionein-1 gene cluster in breast cancer

BACKGROUND: Recent genome-wide analysis has shown that DNA methylation spans long stretches of chromosome regions consisting of clusters of contiguous CpG islands or gene families. Hypermethylation of various gene clusters has been reported in many types of cancer. In this study, we conducted methyl...

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Bibliographic Details
Published in:Clin Epigenetics
Main Authors: Jadhav, Rohit R, Ye, Zhenqing, Huang, Rui-Lan, Liu, Joseph, Hsu, Pei-Yin, Huang, Yi-Wen, Rangel, Leticia B, Lai, Hung-Cheng, Roa, Juan Carlos, Kirma, Nameer B, Huang, Tim Hui-Ming, Jin, Victor X
Format: Artigo
Language:Inglês
Published: BioMed Central 2015
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355986/
https://ncbi.nlm.nih.gov/pubmed/25763113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-015-0045-9
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