Genome-wide DNA methylation analysis reveals estrogen-mediated epigenetic repression of metallothionein-1 gene cluster in breast cancer

BACKGROUND: Recent genome-wide analysis has shown that DNA methylation spans long stretches of chromosome regions consisting of clusters of contiguous CpG islands or gene families. Hypermethylation of various gene clusters has been reported in many types of cancer. In this study, we conducted methyl...

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Detalhes bibliográficos
Publicado no:Clin Epigenetics
Main Authors: Jadhav, Rohit R, Ye, Zhenqing, Huang, Rui-Lan, Liu, Joseph, Hsu, Pei-Yin, Huang, Yi-Wen, Rangel, Leticia B, Lai, Hung-Cheng, Roa, Juan Carlos, Kirma, Nameer B, Huang, Tim Hui-Ming, Jin, Victor X
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355986/
https://ncbi.nlm.nih.gov/pubmed/25763113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-015-0045-9
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