Estrogen-mediated epigenetic repression of large chromosomal regions through DNA looping

The current concept of epigenetic repression is based on one repressor unit corresponding to one silent gene. This notion, however, cannot adequately explain concurrent silencing of multiple loci observed in large chromosome regions. The long-range epigenetic silencing (LRES) can be a frequent occur...

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Detalhes bibliográficos
Main Authors: Hsu, Pei-Yin, Hsu, Hang-Kai, Singer, Gregory A.C., Yan, Pearlly S., Rodriguez, Benjamin A.T., Liu, Joseph C., Weng, Yu-I, Deatherage, Daniel E., Chen, Zhong, Pereira, Julia S., Lopez, Ricardo, Russo, Jose, Wang, Qianben, Lamartiniere, Coral A., Nephew, Kenneth P., Huang, Tim H.-M.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2010
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877570/
https://ncbi.nlm.nih.gov/pubmed/20442245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.101923.109
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