The autism-associated chromatin modifier CHD8 regulates other autism risk genes during human neurodevelopment

Recent studies implicate chromatin modifiers in autism spectrum disorder (ASD) through the identification of recurrent de novo loss of function mutations in affected individuals. ASD risk genes are co-expressed in human midfetal cortex, suggesting that ASD risk genes converge in specific regulatory...

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Publicado no:Nat Commun
Main Authors: Cotney, Justin, Muhle, Rebecca A., Sanders, Stephan J., Liu, Li, Willsey, A. Jeremy, Niu, Wei, Liu, Wenzhong, Klei, Lambertus, Lei, Jing, Yin, Jun, Reilly, Steven K., Tebbenkamp, Andrew T., Bichsel, Candace, Pletikos, Mihovil, Sestan, Nenad, Roeder, Kathryn, State, Matthew W., Devlin, Bernie, Noonan, James P.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355952/
https://ncbi.nlm.nih.gov/pubmed/25752243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7404
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