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N(6)-methyladenosine-dependent RNA structural switches regulate RNA-protein interactions
RNA-binding proteins control many aspects of cellular biology through binding single-stranded RNA binding motifs (RBM)(1-3). However, RBMs can be buried within their local RNA structures(4-7), thus inhibiting RNA-protein interactions. N(6)-methyladenosine (m(6)A), the most abundant and dynamic inter...
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| Veröffentlicht in: | Nature |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4355918/ https://ncbi.nlm.nih.gov/pubmed/25719671 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature14234 |
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