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Detection of germline mutations of hMLH1 and hMSH2 based on cDNA sequencing in China

AIM: To detect the germline mutations of hMLH1 and hMSH2 based on mRNA sequencing to identify hereditary non-polyposis colorectal cancer (HNPCC) families. METHODS: Total RNA was extracted from peripheral blood of 14 members from 12 different families fulfilling Amsterdam criteria II. mRNA of hMLH1 a...

詳細記述

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書誌詳細
出版年:World J Gastroenterol
主要な著者: Wang, Chao-Fu, Zhou, Xiao-Yan, Zhang, Tai-Ming, Sun, Meng-Hong, Shi, Da-Ren
フォーマット: Artigo
言語:Inglês
出版事項: Baishideng Publishing Group Inc 2005
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355754/
https://ncbi.nlm.nih.gov/pubmed/16425354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v11.i42.6620
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