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Detection of germline mutations of hMLH1 and hMSH2 based on cDNA sequencing in China
AIM: To detect the germline mutations of hMLH1 and hMSH2 based on mRNA sequencing to identify hereditary non-polyposis colorectal cancer (HNPCC) families. METHODS: Total RNA was extracted from peripheral blood of 14 members from 12 different families fulfilling Amsterdam criteria II. mRNA of hMLH1 a...
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| Veröffentlicht in: | World J Gastroenterol |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Baishideng Publishing Group Inc
2005
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4355754/ https://ncbi.nlm.nih.gov/pubmed/16425354 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v11.i42.6620 |
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