Polymorphism in LEP and LEPR May Modify Leptin Levels and Represent Risk Factors for Thyroid Cancer

Purpose. To understand the role of polymorphisms in the LEP (rs7799039 and rs2167270) and LEPR (rs1137101 and rs1137100) genes in DTC susceptibility and their effect on leptin levels. Methods. We studied 153 patients with DTC and 234 controls through TaqMan SNP Genotyping and ELISA, comparing these...

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Bibliografske podrobnosti
izdano v:Int J Endocrinol
Main Authors: Marcello, Marjory Alana, Calixto, Antonio Ramos, de Almeida, Jacqueline Fatima Martins, Martins, Mariana Bonjiorno, Cunha, Lucas Leite, Cavalari, Camila Ayume Amano, Etchebehere, Elba C. S., da Assumpção, Ligia Vera Montalli, Geloneze, Bruno, Carvalho, Andre Lopes, Ward, Laura Sterian
Format: Artigo
Jezik:Inglês
Izdano: Hindawi Publishing Corporation 2015
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355553/
https://ncbi.nlm.nih.gov/pubmed/25810718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/173218
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