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PCTK1 Regulates Integrin-Dependent Spindle Orientation via Protein Kinase A Regulatory Subunit KAP0 and Myosin X

Integrin-dependent cell-extracellular matrix (ECM) adhesion is a determinant of spindle orientation. However, the signaling pathways that couple integrins to spindle orientation remain elusive. Here, we show that PCTAIRE-1 kinase (PCTK1), a member of the cyclin-dependent kinases (CDKs) whose functio...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Iwano, Sayaka, Satou, Ayaka, Matsumura, Shigeru, Sugiyama, Naoyuki, Ishihama, Yasushi, Toyoshima, Fumiko
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355539/
https://ncbi.nlm.nih.gov/pubmed/25605337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01017-14
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