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Innate Immune Response to Streptococcus pyogenes Depends on the Combined Activation of TLR13 and TLR2
Innate immune recognition of the major human-specific Gram-positive pathogen Streptococcus pyogenes is not understood. Here we show that mice employ Toll-like receptor (TLR) 2- and TLR13-mediated recognition of S. pyogenes. These TLR pathways are non-redundant in the in vivo context of animal infect...
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| Опубликовано в: : | PLoS One |
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| Главные авторы: | , , , , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4355416/ https://ncbi.nlm.nih.gov/pubmed/25756897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0119727 |
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