Group A Streptococcus Activates Type I Interferon Production and MyD88-dependent Signaling without Involvement of TLR2, TLR4, and TLR9

Bacterial pathogens are recognized by the innate immune system through pattern recognition receptors, such as Toll-like receptors (TLRs). Engagement of TLRs triggers signaling cascades that launch innate immune responses. Activation of MAPKs and NF-κB, elements of the major signaling pathways induce...

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Detalhes bibliográficos
Main Authors: Gratz, Nina, Siller, Maria, Schaljo, Barbara, Pirzada, Zaid A., Gattermeier, Irene, Vojtek, Ivo, Kirschning, Carsten J., Wagner, Hermann, Akira, Shizuo, Charpentier, Emmanuelle, Kovarik, Pavel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Mechanisms of Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2459277/
https://ncbi.nlm.nih.gov/pubmed/18480050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M802848200
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