Granzyme B Expression is Enhanced in Human Monocytes by TLR8 Agonists and Contributes to ADCC()

Fcγ receptors (FcγR) are critical mediators of monoclonal antibody cancer therapies, as they drive cytotoxic processes upon binding of effector cells to opsonized targets. Along with natural killer (NK) cells, monocytes are also known to destroy antibody-coated targets via antibody-dependent cellula...

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Detaylı Bibliyografya
Yayımlandı:J Immunol
Asıl Yazarlar: Elavazhagan, Saranya, Fatehchand, Kavin, Santhanam, Vikram, Fang, Huiqing, Ren, Li, Gautam, Shalini, Reader, Brenda, Mo, Xiaokui, Cheney, Carolyn, Briercheck, Edward, Vasilakos, John P., Dietsch, Gregory N., Hershberg, Robert M., Caligiuri, Michael, Byrd, John C., Butchar, Jonathan P., Tridandapani, Susheela
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355383/
https://ncbi.nlm.nih.gov/pubmed/25667415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402316
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