Granzyme B Expression is Enhanced in Human Monocytes by TLR8 Agonists and Contributes to ADCC()

Fcγ receptors (FcγR) are critical mediators of monoclonal antibody cancer therapies, as they drive cytotoxic processes upon binding of effector cells to opsonized targets. Along with natural killer (NK) cells, monocytes are also known to destroy antibody-coated targets via antibody-dependent cellula...

詳細記述

保存先:
書誌詳細
出版年:J Immunol
主要な著者: Elavazhagan, Saranya, Fatehchand, Kavin, Santhanam, Vikram, Fang, Huiqing, Ren, Li, Gautam, Shalini, Reader, Brenda, Mo, Xiaokui, Cheney, Carolyn, Briercheck, Edward, Vasilakos, John P., Dietsch, Gregory N., Hershberg, Robert M., Caligiuri, Michael, Byrd, John C., Butchar, Jonathan P., Tridandapani, Susheela
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355383/
https://ncbi.nlm.nih.gov/pubmed/25667415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402316
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