Lysine Demethylase KDM4A Associates with Translation Machinery and Regulates Protein Synthesis

Chromatin modifying enzymes are predominantly nuclear; however, these factors are also localized to the cytoplasm and very little is known about their role in this compartment. In this report, we reveal a non-chromatin linked role for the lysine-specific demethylase KDM4A. We demonstrate that KDM4A...

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Pubblicato in:Cancer Discov
Autori principali: Van Rechem, Capucine, Black, Joshua C., Boukhali, Myriam, Aryee, Martin J., Gräslund, Susanne, Haas, Wilhelm, Benes, Cyril H., Whetstine, Johnathan R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355328/
https://ncbi.nlm.nih.gov/pubmed/25564516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-14-1326
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