κ Opioid Receptors in the Nucleus Accumbens Shell Mediate Escalation of Methamphetamine Intake

Given that the κ opioid receptor (KOR) system has been implicated in psychostimulant abuse, we evaluated whether the selective KOR antagonist norbinaltorphimine dihydrochloride (nor-BNI) would attenuate the escalation of methamphetamine (METH) intake in an extended-access self-administration model....

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Bibliographic Details
Published in:J Neurosci
Main Authors: Whitfield, Timothy W., Schlosburg, Joel E., Wee, Sunmee, Gould, Adam, George, Olivier, Grant, Yanabel, Zamora-Martinez, Eva R., Edwards, Scott, Crawford, Elena, Vendruscolo, Leandro F., Koob, George F.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355200/
https://ncbi.nlm.nih.gov/pubmed/25762676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1978-13.2015
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