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The role of the dynorphin–κ opioid system in the reinforcing effects of drugs of abuse
BACKGROUND: Initial hypotheses regarding the role of the κ opioid system in drug addiction suggested that κ receptor stimulation had anti-addictive effects. However, recent research suggests that κ receptor antagonists may reverse motivational aspects of dependence. In the present review, we revisit...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2879894/ https://ncbi.nlm.nih.gov/pubmed/20352414 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-010-1825-8 |
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