Cockayne Syndrome Group B (Csb) and Group A (Csa) Deficiencies Predispose to Hearing Loss and Cochlear Hair Cell Degeneration in Mice

Sensory hair cells in the cochlea, like most neuronal populations that are postmitotic, terminally differentiated, and non-regenerating, depend on robust mechanisms of self-renewal for lifelong survival. We report that hair cell homeostasis requires a specific sub-branch of the DNA damage nucleotide...

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Detalles Bibliográficos
Publicado en:J Neurosci
Main Authors: Nagtegaal, A. Paul, Rainey, Robert N., van der Pluijm, Ingrid, Brandt, Renata M.C., van der Horst, Gijsbertus T.J., Borst, J. Gerard G., Segil, Neil
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2015
Assuntos:
Brief Communications
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355199/
https://ncbi.nlm.nih.gov/pubmed/25762674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5063-14.2015
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