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Transgene-derived overexpression of miR-17-92 in CD8(+) T-cells confers enhanced cytotoxic activity
MicroRNAs (miRs) play important roles in regulation of a variety of cell functions, including immune responses. We have previously demonstrated that miR-17-92 expression in T-cells enhances Th1 phenotype and provides a long-term protection against glioblastoma when co-expressed as a transgene in T-c...
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| Veröffentlicht in: | Biochem Biophys Res Commun |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4355048/ https://ncbi.nlm.nih.gov/pubmed/25677619 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2015.02.003 |
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