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Transgene-derived overexpression of miR-17-92 in CD8(+) T-cells confers enhanced cytotoxic activity

MicroRNAs (miRs) play important roles in regulation of a variety of cell functions, including immune responses. We have previously demonstrated that miR-17-92 expression in T-cells enhances Th1 phenotype and provides a long-term protection against glioblastoma when co-expressed as a transgene in T-c...

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Bibliografiske detaljer
Udgivet i:Biochem Biophys Res Commun
Main Authors: Kosaka, Akemi, Ohkuri, Takayuki, Ikeura, Maki, Kohanbash, Gary, Okada, Hideho
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355048/
https://ncbi.nlm.nih.gov/pubmed/25677619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2015.02.003
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