Serum progranulin levels are elevated in dermatomyositis patients with acute interstitial lung disease, predicting prognosis

INTRODUCTION: Progranulin (PGRN), a pleiotropic growth factor, has emerged as an immunoregulatory molecule. Because the roles of PGRN in dermatomyositis (DM) are still unknown, we investigated whether serum PGRN levels are associated with disease activity and prognosis in DM patients, particularly i...

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Veröffentlicht in:Arthritis Res Ther
Hauptverfasser: Tanaka, Atsushi, Tsukamoto, Hiroshi, Mitoma, Hiroki, Kiyohara, Chikako, Ueda, Naoyasu, Ayano, Masahiro, Ohta, Shun-ichiro, Kimoto, Yasutaka, Akahoshi, Mitsuteru, Arinobu, Yojiro, Niiro, Hiroaki, Tada, Yoshifumi, Horiuchi, Takahiko, Akashi, Koichi
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4354987/
https://ncbi.nlm.nih.gov/pubmed/25888887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-015-0547-z
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