Serum progranulin levels are elevated in dermatomyositis patients with acute interstitial lung disease, predicting prognosis

INTRODUCTION: Progranulin (PGRN), a pleiotropic growth factor, has emerged as an immunoregulatory molecule. Because the roles of PGRN in dermatomyositis (DM) are still unknown, we investigated whether serum PGRN levels are associated with disease activity and prognosis in DM patients, particularly i...

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Gepubliceerd in:Arthritis Res Ther
Hoofdauteurs: Tanaka, Atsushi, Tsukamoto, Hiroshi, Mitoma, Hiroki, Kiyohara, Chikako, Ueda, Naoyasu, Ayano, Masahiro, Ohta, Shun-ichiro, Kimoto, Yasutaka, Akahoshi, Mitsuteru, Arinobu, Yojiro, Niiro, Hiroaki, Tada, Yoshifumi, Horiuchi, Takahiko, Akashi, Koichi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2015
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4354987/
https://ncbi.nlm.nih.gov/pubmed/25888887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-015-0547-z
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