Serum progranulin levels are elevated in dermatomyositis patients with acute interstitial lung disease, predicting prognosis

INTRODUCTION: Progranulin (PGRN), a pleiotropic growth factor, has emerged as an immunoregulatory molecule. Because the roles of PGRN in dermatomyositis (DM) are still unknown, we investigated whether serum PGRN levels are associated with disease activity and prognosis in DM patients, particularly i...

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Publicat a:Arthritis Res Ther
Autors principals: Tanaka, Atsushi, Tsukamoto, Hiroshi, Mitoma, Hiroki, Kiyohara, Chikako, Ueda, Naoyasu, Ayano, Masahiro, Ohta, Shun-ichiro, Kimoto, Yasutaka, Akahoshi, Mitsuteru, Arinobu, Yojiro, Niiro, Hiroaki, Tada, Yoshifumi, Horiuchi, Takahiko, Akashi, Koichi
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4354987/
https://ncbi.nlm.nih.gov/pubmed/25888887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-015-0547-z
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