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RIM-Binding Protein Links Synaptic Homeostasis to the Stabilization and Replenishment of High Release Probability Vesicles
Here we define activities of RIM-Binding Protein (RBP) that are essential for baseline neurotransmission and presynaptic homeostatic plasticity. At baseline, rbp mutants have a ~10-fold decrease in the apparent Ca(2+) sensitivity of release that we attribute to 1) impaired presynaptic Ca(2+) influx,...
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| Publicado no: | Neuron |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4354699/ https://ncbi.nlm.nih.gov/pubmed/25704950 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2015.01.024 |
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