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Prion protein facilitates synaptic vesicle release by enhancing release probability

The cellular prion protein (PrP(C)) has been implicated in several neurodegenerative diseases as a result of protein misfolding. In humans, prion disease occurs typically with a sporadic origin where uncharacterized mechanisms induce spontaneous PrP(C) misfolding leading to neurotoxic PrP-scrapie fo...

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Podrobná bibliografie
Hlavní autoři: Robinson, Susan W., Nugent, Marie L., Dinsdale, David, Steinert, Joern R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4119408/
https://ncbi.nlm.nih.gov/pubmed/24722203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu171
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