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Prion protein facilitates synaptic vesicle release by enhancing release probability
The cellular prion protein (PrP(C)) has been implicated in several neurodegenerative diseases as a result of protein misfolding. In humans, prion disease occurs typically with a sporadic origin where uncharacterized mechanisms induce spontaneous PrP(C) misfolding leading to neurotoxic PrP-scrapie fo...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2014
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4119408/ https://ncbi.nlm.nih.gov/pubmed/24722203 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu171 |
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