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The Bioconjugation and Radiosynthesis of (89)Zr-DFO-labeled Antibodies

The exceptional affinity, specificity, and selectivity of antibodies make them extraordinarily attractive vectors for tumor-targeted PET radiopharmaceuticals. Due to their multi-day biological half-life, antibodies must be labeled with positron-emitting radionuclides with relatively long physical de...

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Bibliografiske detaljer
Udgivet i:J Vis Exp
Main Authors: Zeglis, Brian M., Lewis, Jason S.
Format: Artigo
Sprog:Inglês
Udgivet: MyJove Corporation 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4354640/
https://ncbi.nlm.nih.gov/pubmed/25741890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/52521
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