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An Ex vivo Model of an Oligodendrocyte-directed T-Cell Attack in Acute Brain Slices
Death of oligodendrocytes accompanied by destruction of neurons and axons are typical histopathological findings in cortical and subcortical grey matter lesions in inflammatory demyelinating disorders like multiple sclerosis (MS). In these disorders, mainly CD8(+) T-cells of putative specificity for...
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| Udgivet i: | J Vis Exp |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
MyJove Corporation
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4354573/ https://ncbi.nlm.nih.gov/pubmed/25741800 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/52205 |
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