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Coupling of T cell receptor specificity to natural killer T cell development by bivalent histone H3 methylation
The fidelity of T cell immunity depends greatly on coupling T cell receptor signaling with specific T cell effector functions. Here, we describe a chromatin-based mechanism that enables integration of TCR specificity into definite T cell lineage commitment. Using natural killer T cells (iNKT cell) a...
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| Yayımlandı: | J Exp Med |
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| Asıl Yazarlar: | , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
The Rockefeller University Press
2015
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4354372/ https://ncbi.nlm.nih.gov/pubmed/25687282 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20141499 |
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