CD160 is essential for NK-mediated IFN-γ production

NK-derived cytokines play important roles for natural killer (NK) function, but how the cytokines are regulated is poorly understood. CD160 is expressed on activated NK or T cells in humans but its function is unknown. We generated CD160-deficient mice to probe its function. Although CD160(−/−) mice...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Exp Med
Main Authors: Tu, Tony C., Brown, Nicholas K., Kim, Tae-Jin, Wroblewska, Joanna, Yang, Xuanming, Guo, Xiaohuan, Lee, Seoyun Hyunji, Kumar, Vinay, Lee, Kyung-Mi, Fu, Yang-Xin
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2015
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4354368/
https://ncbi.nlm.nih.gov/pubmed/25711213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20131601
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