IFN-γ-dependent NK cell activation is essential to metastasis suppression by engineered Salmonella

Metastasis accounts for 90% of cancer-related deaths and, currently, there are no effective clinical therapies to block the metastatic cascade. A need to develop novel therapies specifically targeting fundamental metastasis processes remains urgent. Here, we demonstrate that Salmonella YB1, an engin...

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Udgivet i:Nat Commun
Main Authors: Lin, Qiubin, Rong, Li, Jia, Xian, Li, Renhao, Yu, Bin, Hu, Jingchu, Luo, Xiao, Badea, S. R., Xu, Chen, Fu, Guofeng, Lai, Kejiong, Lee, Ming-chun, Zhang, Baozhong, Gong, Huarui, Zhou, Nan, Chen, Xiao Lei, Lin, Shu-hai, Fu, Guo, Huang, Jian-Dong
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8099885/
https://ncbi.nlm.nih.gov/pubmed/33953170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22755-3
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