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Detection of Intestinal Cancer by local, topical application of a Quenched Fluorescence Probe for Cysteine Cathepsins

Early detection of colonic polyps can prevent up to 90% of colorectal cancer deaths. Conventional colonoscopy readily detects the majority of pre-malignant lesions, which exhibit raised morphology. However, lesions that are flat and depressed are often undetected using this method. Therefore, there...

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Detalhes bibliográficos
Publicado no:Chem Biol
Main Authors: Segal, Ehud, Prestwood, Tyler R., van der Linden, Wouter A., Carmi, Yaron, Bhattacharya, Nupur, Withana, Nimail, Verdoes, Martijn, Habtezion, Aida, Engleman, Edgar G., Bogyo, Matthew
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4353655/
https://ncbi.nlm.nih.gov/pubmed/25579207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2014.11.008
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