The TLQP-21 Peptide Activates the G-protein-coupled receptor C3aR1 via a Folding-upon-Binding Mechanism

TLQP-21, a VGF-encoded peptide is emerging as a novel target for obesity-associated disorders. TLQP-21 is found in the sympathetic nerve terminals in the adipose tissue and targets the G-protein-coupled-receptor (GPCR) Complement-3a-Receptor1 (C3aR1). So far, the mechanisms of TLQP-21-induced recept...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Structure
Main Authors: Cero, Cheryl, Vostrikov, Vitaly V., Verardi, Raffaello, Severini, Cinzia, Gopinath, Tata, Braun, Patrick D., Sassano, Maria F., Gurney, Allison, Roth, Bryan L., Vulchanova, Lucy, Possenti, Roberta, Veglia, Gianluigi, Bartolomucci, Alessandro
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4353613/
https://ncbi.nlm.nih.gov/pubmed/25456411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2014.10.001
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados