A comparison of the cytogenetic alterations and global DNA hypomethylation induced by the benzene metabolite, hydroquinone, with those induced by melphalan and etoposide

Specific cytogenetic alterations and changes in DNA methylation are involved in leukemogenesis. Benzene, an established human leukemogen, is known to induce cytogenetic changes through its active metabolites including hydroquinone (HQ), but the specific alterations have not been fully characterized....

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Publicado en:Leukemia
Main Authors: Ji, Z, Zhang, L, Peng, V., Ren, X, McHale, CM, Smith, MT
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4353491/
https://ncbi.nlm.nih.gov/pubmed/20339439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2010.43
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