Загрузка...
Damage-induced BRCA1 phosphorylation by Chk2 contributes to the timing of end resection
The BRCA1 tumor suppressor plays an important role in homologous recombination (HR)-mediated DNA double-strand-break (DSB) repair. BRCA1 is phosphorylated by Chk2 kinase upon γ-irradiation, but the role of Chk2 phosphorylation is not understood. Here, we report that abrogation of Chk2 phosphorylatio...
Сохранить в:
| Опубликовано в: : | Cell Cycle |
|---|---|
| Главные авторы: | , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Taylor & Francis
2015
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4353239/ https://ncbi.nlm.nih.gov/pubmed/25659039 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.972901 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|